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From143US$ /night
Check-in
11Dec2025Select date
Check-out
12Dec2025Select date
Rooms and Guests2 Guests, 1 Room
Key details

Hotel Overview

1528 Locust Street, Saint Louis, Missouri, United States, 63103
-
Close to the Gateway Arch
Perfect
8.4
8.9
/10
4.2
4.2
/5

21C Museum Hotel St Louis - 4-star art-focused hotel near St Louis Gateway Arch

Located in Downtown St. Louis, this hotel is a 15-minute walk from Union Station and 2.5 km from St Louis Gateway Arch. The property features a 24-hour fitness center, historic indoor pool, and an on-site restaurant serving Spanish-inspired tapas. Guests have access to free Wi-Fi, original artwork by Missouri-based artists, and pet-friendly rooms. The hotel includes a contemporary art museum open 24/7. St Louis Lambert International Airport is the nearest airport, located approximately 20 km away.

Additional perks of the hotel

Locust Street Athletic and Swim Club with sauna and steam rooms

Small-group training sessions and personal training available

Monthly Coffee Talks on social impact and equity

Free museum tours and curated art exhibitions

On-site Idol Wolf restaurant with seasonal Midwestern-Spanish cuisine

Rooms overview

The hotel offers several room types, including Deluxe King, Luxury Double Queen, and Corner King Suite. All rooms feature air conditioning, a seating area, a wardrobe, a safe deposit box, and a flat-screen TV with streaming services. The 21c King Suite is a two-story duplex with a living and dining area, fireplace, and kitchenette. The Luxury King Suite includes a separate living area with a table and office, plus a bathroom with dual sink vanity and soaking tub.

Other conveniences

Malin+Goetz bath amenities and bathrobes

Northwest Coffee in rooms

50'' HDTV flat-screen television

Alarm clock/docking station

Laundry service and in-room dining available

Must-do experiences

  • Stroll through CityGarden for stunning public art and green space.
  • Savor gooey butter cake at Billy G's for a local dessert delight.
  • Visit the Missouri Botanical Garden for beautiful landscapes and flora.
  • Explore the historic Soulard Market for fresh produce and local goods.
  • Catch a show at The Fabulous Fox Theatre for an unforgettable night.
View all

Choose Your Room

Our listed hotels offer a variety of room types—double rooms, family suites, or deluxe options—all with features like breakfast, flexible cancellation policies, and exclusive deals.
Deluxe King Room
2 persons
29 m² 
1 King-size bed
Shower
Heating
Deluxe King Suite Roll Shower Accessible
2 persons
47 m² 
1 King-size bed
Shower
Heating
Loft Two Queen Beds
2 persons
40 m² 
2 King Size Beds
Shower
Heating
Deluxe King Room Accessible
2 persons
29 m² 
1 King-size bed
Shower
Heating
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Room Rates & Availability Tracker

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Amenities

Thoughtful hotel amenities for a comfortable stay

General

  • No smoking on site
  • Free Wi-Fi
  • Safe deposit box
  • 24-hour reception
  • VIP check-in/ -out
  • Pets allowed
  • Rooms/ Facilities for disabled
  • Wheelchair access
  • 24-hour security
  • Luggage storage
  • Locker room
  • Allergy-free rooms
  • Lift
  • ATM/Cash machine
  • Coffee shop
  • Vending machines
  • Smoke detectors
  • Fire extinguishers
  • Key card access

Sports & Fitness

  • Fitness centre
  • Billiard tables
  • Yoga class

Services

  • Valet parking
  • Room service
  • Housekeeping
  • Laundry
  • Dry cleaning
  • Welcome drink

Dining

  • Restaurant
  • Bar/ Lounge area
  • Special diet menus

Business

  • Business centre
  • Meeting/ Banquet facilities

Children

  • Cots
  • Board games
  • Game room

Facilities for people with disabilities

  • Toilet for disabled

Spa & Leisure

  • Indoor swimming pool
  • Leisure/ TV room
  • Spa & wellness centre
  • Steam room
  • Jacuzzi
  • Massage

Room features

  • Wi-Fi in rooms
  • Air conditioning
  • Heating
  • Soundproofed rooms
  • Sitting area
  • Terrace
  • Garden furniture
  • Ironing facilities

Bathroom

  • Free toiletries

Media

  • Flat-screen TV
  • Direct dial telephone
  • AM/FM alarm clock
Show more

Hotel Location

1528 Locust Street, Saint Louis, Missouri, United States, 63103
Map view
1528 Locust Street, Saint Louis, Missouri, United States, 63103
Nearby
Museum
City Museum
520 m
Museum
Campbell House Museum
90 m
Church
Christ Church Cathedral
430 m
1315 Chestnut St
Soldiers Memorial Military Museum
590 m
Aquarium
World Aquarium
400 m
Church
Centenary United Methodist Church
190 m
Night club
The Boom Boom Room
280 m
13th and Locust
Lucas Garden Park
350 m
Restaurants
The Last Kitchen
360 m
1501 Washington Ave Inside The Last Hotel
Red Oak Biscuits
310 m
1330 Washington Ave
Nara Cafe and Hookah Lounge
310 m
1326 Washington Ave
Flannery's
380 m
1324 Washington Ave
Rooftop Cafe at City Museum
400 m
701 N 15th St Fl 11
Lucas Park Grille
440 m
1234 Washington Avenue
Rosalita's Cantina
480 m
1235 Washington Avenue
Blondie's Coffee
450 m
1301 Washington Ave
Imo's Pizza
410 m
1828 Washington Ave
Papa John's Pizza
610 m
201 N Tucker Blvd Ste E
Bootleggin' BBQ
650 m
1933 Washington Ave
Explore Saint Louis
Local Highlights
Top Attractions
Activities
Dining
Entertainment
City Museum
City Museum
5 minutes walking
A whimsical space featuring interactive art installations and play areas, perfect for families and curious minds.
Campbell House Museum
Campbell House Museum
2 minutes walking
An exquisite house museum showcasing 19th-century art and furnishings, offering guided tours for history enthusiasts.
The Gateway Arch
The Gateway Arch
25 minutes walking
Iconic national monument offering stunning views of St. Louis; guided tours available for an in-depth experience.
Scott Joplin House State Historic Site
Scott Joplin House State Historic Site
15 minutes walking
Historic home of the ragtime composer with guided tours focusing on musical history and Joplin's legacy.
Biking along the Riverfront
5 minutes drive
Scenic biking trails offer thrilling rides with river views, bike rentals accessible nearby for convenience.
Yoga in the Park
8 minutes walking
Weekly outdoor yoga sessions available in nearby parks, great for relaxation and wellness enthusiasts.
The Last Kitchen
The Last Kitchen
5 minutes walking
Contemporary American fare in a casual setting; known for hearty brunches and local craft beers.
Nara Cafe and Hookah Lounge
Nara Cafe and Hookah Lounge
4 minutes walking
Chill atmosphere featuring Mediterranean cuisine and exotic hookah flavors; vegetarian options available.
Rooftop Cafe at City Museum
Rooftop Cafe at City Museum
5 minutes walking
Unique dining experience with panoramic city views; seasonal menu featuring locally sourced ingredients.
Stifel Theatre
Stifel Theatre
8 minutes walking
Renowned venue hosting a variety of performances, from concerts to comedy; a great spot for evening entertainment.
National Blues Museum
National Blues Museum
16 minutes walking
Celebrating St. Louis' blues roots with engaging exhibits and live performances; perfect for music lovers.
Transportation Tips
City Centre
Saint Louis8 min  ·  600 m
Airports
Lambert (STL)33 min  ·  21.8 km
MidAmerica St. Louis/Scott Air Force Base (BLV)62 min  ·  40.8 km
Train
Union Station9 min  ·  700 m
Bus
Bus stop3 min  ·  200 m
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Property information and rules
Check-in
from 16:00-23:59
Check-out
until 11 am
Guest Parking
No parking available.
Internet
is available in for free.
Pets
Pets are allowed on request.
Number of floors:
10
Number of rooms:
137
Questions of the users
About 21C Museum Hotel St Louis
Is there an additional cost associated with parking at 21C Museum Hotel St Louis during my stay?
27 February 2024
Valet parking is available, with overnight charges at $45. For shorter stays, the rates are $10 for up to 4 hours and $20 for 4 to 8 hours.
Are there parking options that ensure the safety of my vehicle at 21C Museum Hotel St Louis, and what is the cancellation policy?
14 March 2024
Secured valet parking is offered for guests. Cancellation policies may vary based on the type of booking; details can typically be found at the point of reservation.
Do guests have to pay extra for breakfast at the restaurant Goodpress?
5 April 2024
Breakfast is available for an additional charge; please refer to the menu for details.
Is internet access provided for guests at 21C Museum Hotel St Louis?
20 April 2024
Complimentary Wi-Fi is offered to all guests throughout the hotel.
Can guests use the spa for massages and other treatments at 21C Museum Hotel St Louis?
15 May 2024
Yes, the spa is operational and offers a variety of massages and treatments. Booking can be done through the LSAC scheduling platform.
What are the operating hours for the spa and the fitness center at 21C Museum Hotel St Louis?
30 June 2024
The spa operates Monday to Friday from 9:00 AM to 9:00 PM, and Saturday to Sunday from 8:00 AM to 4:00 PM. The fitness center is accessible 24/7.
What is the minimum age requirement for checking in at 21C Museum Hotel St Louis?
12 July 2024
The minimum age for check-in is 21.
How is 21C Museum Hotel St Louis involved in community support?
28 September 2024
The hotel partners with monthly nonprofit organizations, putting a spotlight on community impact through various initiatives.
Can I experience local art installations during my stay at 21C Museum Hotel St Louis?
19 October 2024
Yes, the hotel features dynamic and thought-provoking art installations that are accessible to guests at all times, free of charge.
What unique dining experiences can guests expect from the restaurant at 21C Museum Hotel St Louis?
21 November 2024
Idol Wolf offers a creative tapas-style dining experience, perfect for enjoying shared meals that blend Spanish classics with local flavors.

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